Research suggests that this powerful psychoactive chemical could be produced within our brains.

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N, N-dimethyltryptamine (DMT) is one of the most powerful psychedelic compounds in the world. It’s the psychoactive ingredient in Ayahuasca, a brew mixture of the Banisteriopsis caapi vine and the leaves of the Psychotria Viridis bush, traditionally used by indigenous people for sacred religious ceremonies.

Scientific analysis of the B. caapi vine showed that it is rich in β-carbolines alkaloids (B-CA), which protect the DMT from degrading in the intestine and liver, while the P. Viridis leaves contain the psychoactive substance DMT.

DMT belongs to a class of serotonergic psychedelics like psilocybin and lysergic acid diethylamide (LSD), eliciting a wide…


This is why psychedelics are so effective for treating mental illnesses.

Psilocybin is one of the so-called classic psychedelics being studied for its potential therapeutic benefits. (Image credit: Shutterstock.)

What if I told you that treating a variety of mental diseases with psychedelics is far more effective than the current mental health treatments and commonly prescribed antidepressants?

You probably wouldn’t believe me.

However, it’s true!

A surplus of new evidence supports the claim that psychedelics may produce acute, often after just 1 psychedelic ‘trip’, and long-term beneficial outcomes in mental illnesses, e.g., depression, anxiety, post-traumatic stress disorder (PTSD), obsessive-compulsive disorder, and even tobacco and alcohol misuse. In other words, psychiatry may never be the same. But what are these powerful psychoactive compounds? Why did scientific interest begin its revival…


Research suggests ibogaine therapy can eliminate withdrawal symptoms and cravings towards drugs in struggling addicts.

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Followers of the Bwiti religion in the West Africa nation of Gabon have used ibogaine for centuries in healing and spiritual rituals. Ibogaine is a naturally occurring psychoactive chemical derived from the root bark of Iboga — Tabernathe iboga. While ibogaine is a mild stimulant in small doses, in larger doses it induces a psychedelic trip more intense and longer-lasting (up to 36 hours) than LSD or psilocybin mushrooms.

Although the drug can lead to some short-term effects like anxiety during or after the experienced hallucinations, it has been proposed as a potential treatment to devastating addiction problems to substances…


A study suggests excess coffee consumption could increase the risk of dementia by 53%.

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For most of us, a quick coffee is a favorite first-order of the day to give your morning energy levels a boost. However, new research from the University of South Australia shows that too much coffee is linked to increased dementia risk and smaller brain volume.

Coffee is one of the most consumed beverages in the world after water, with global consumption exceeding 9 billion kilograms each year. Coffee contains caffeine which stimulates the central nervous system. …


K.Vita reduced seizures by up to 50% in children and adults with drug-resistant epilepsy.

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The first clinical trial of a new dietary treatment called K.Vita, an oral dietary substance based on the ketogenic diet, for children and adults with severe forms of epilepsy has been successfully completed.

Epilepsy affects over 50 million people worldwide and approximately a third of people diagnosed with epilepsy do not have seizures adequately controlled by current treatments.

Epilepsy is a central nervous system — neurological — disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of awareness.

Seizure symptoms can vary widely. Some people with epilepsy simply stare blankly for…


And explaining the simple science-backed methods that can help you burn up an extra minimum of 800 calories each day.

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With roughly two out of three U.S. adults are overweight or obese (69 percent) and one out of three is obese (36 percent), and the numbers are even rising since the Covid ’19 pandemic, it is fair to say that the U.S.A. deals with an epidemic of obesity.

Many people nowadays struggle to lose fat or maintaining their weight in general. Before diving deeper into the neuroscience for fat loss, I have to acknowledge upfront the simple, but important law i.e., the core truth of metabolic science:

Calories ingested versus calories burned is the fundamental and most important formula for…


How taking short breaks may help our brains learn new skills faster.

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“Practice makes perfect” is a popular phrase used to emphasize the importance of practice in acquiring and perfecting skills. During distributed practices — cycles of alternating practice and rest periods — consolidation of skill is greater than when the same total amount of practice is performed over longer continuous blocks (massed practice).

So we can say that “much, if not all” skill learning occurs offline during rest rather than during actual practice. This rapid form of skill memory consolidation, micro-offline gains, suggests that it develops over a much shorter timescale than previously thought. …


This science-based tool can get you out of bed earlier.

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Did you know the eyes aren’t just a part of the brain but they really are the brain?

The human eye is part of the sensory nervous system and through the years of evolution, this sense organ is pushed through the skull connecting the internal system with the outside world. The brain uses signal information from the eyes to elicit the perception of color, depth, movement, shape, and other features.

The retina of the eye consists of photoreceptive cells, i.e., rod and cone cells which can detect visible light and send this information to the brain, and photosensitive ganglion cells


Our perceived reality is constructed by patterns of activity from neurons.

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Neuroscientists at Stanford University School of Medicine found that stimulating small subsets of neurons in the brains of mice generates a perception of something that isn’t really there — an illusion or hallucination.

Ok, this sounds really creepy so I will explain the findings of this research carefully.

Back in 2019, the findings of the paper titled, “Cortical layer-specific critical dynamics triggering perception”, were published in the scientific journal Science.

The researchers used a technique called optogenetics, a technology that uses pulses of light to stimulate individual neurons in the visual cortex of mice to generate an illusory image. …


This science-based tool makes you relaxed and calms you down in real-time.

Photo by Eugene Zhyvchik on Unsplash

It’s Tuesday morning, a few minutes before you have to give a talk on stage. 400 people are in the audience. Normally, you don’t experience any anxiety or stress. But giving a talk to this many people…

The nervousness is coming. Your heart is beating faster, your blood pressure is rising, your breathing quickens increasing your alertness and energy, your palms are starting to sweat, your view is getting narrower, your body starts to tremble and you’re starting to realize the nervousness is taking over your mind and body. There’s no time to calm down your mind and body by…

Ruben Bouma

MSc student | Neurosciences | Psychedelics | Biomedical Sciences | Psychology

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